This is a manuscript on medicine and drugs written by Robert Abraham in 1825 in Carlisle and London.
This manuscript comprises three sections, each including an index:
- Part First. "An Essay on the Nature, Value, and Utility of Theory", starting a few pages before p. 1;
- Part Second. "An Enquiry &c.' into the nature of narcotics, hypnotics, sleep, coma, mania, & idiocy", starting on p. 91;
- Part Third. "An examination of various chemical substances and their effects on the body including, Alcohol, Nitrous Oxide, Oxide of Arsenic, Tobacco, Digitalis, Belladonna, etc.", starting on p. 257.
Abraham worked within the time-honoured tradition of self-experimentation: he ingested various substances including nitrous oxide, sulphuric aether, etc. and recorded their intoxicating, hallucinogenic, or other effects. This ambitious work combines theory, experimentation, and scientific practice.... It is crammed with Abraham's revisions, corrections, and additions throughout, it is a testament to the young Abraham's capacious and inquiring mind forever in search of new discoveries.