The material in the collection consists of:
- - at E94.90: a letter from Charles Wyville Thomson written on 2 June 1850 at the home of the Reverend Ainslie and addressed to 'My Dear Sir' - it refers to how he had met with a kind reception from Mr. and Mrs. Ainslie who 'pressed him to dine with them and to take a bed at their home', and how the following day they were to take him to Sir David Brewster's - the letter goes on to say that 'The Chair is not yet filled up, and no one is spoken of as likely to fill it' - it mentions that the Marquis of Ailsa is the Patron and that 'He has acceded to the change being made from a Chair of Civil to one of Natural History'.
- - at E2000.07: a collection of circa 30 letters covering the period 1841-1874 mostly to Charles Wyville Thomson including: those from Geo. Robertson, Edinburgh, and from Cork, Ireland; from R. Redfern; from R. Davison and C.P.Nichol - also a small number from Thomson to Mrs. Thomson and to his son - also an accounts sheet from thomson to Glen and Henderson 1841-1845
- - at E2002.20: a letter from Charles Wyville Thomson written 17 March n.y. at Strandtown, Belfast, to the Secretary of the Palaeontographical Society saying that he and Dr. W.B.Carpenter (1813-1885) have been working on papers for the Philosophical Transactions of the Royal Society and that his own paper 'will form the basis of the natural History introduction to the Monog: of the Crinoids' - he also refers to Marsupites belonging to the Palaeozoic group 'not Comatula'