In 1948, with the advent of the National Health Service, the hospitals in Nottinghamshire were grouped under the Sheffield Regional Hospital Board. The large area covered by the Regional Board included Derby, Leicester and Lincoln in addition to Sheffield and Rotherham. Several hospitals in Nottingham, including the General Hospital, the Children's and Women's Hospitals, all came under the authority of the Nottingham No. 1 Hospital Management Committee. In 1970 its title changed to the Nottingham University Hospital Management Committee, and in 1974 it became the Nottinghamshire Area Health Authority (Teaching) South Nottingham District.
In the 1974 reorganisation of the health service, following the White Paper of 1972, the Trent Regional Health Authority came into being, replacing the former Sheffield Regional Hospital Board. The new Trent Region used Fulwood House in Sheffield as its main headquarters, the premises occupied since 1948 by the Sheffield Regional Hospital Board. The 1974 reorganization brought hospitals under the control of Area Health Authorities accountable to Regional Health Authorities. Within the Trent Region the former University Hospital Management Committee was replaced by the Nottinghamshire Area Health Authority (Teaching) South Nottingham District, which was itself superceded in 1982 by the Nottingham Health Authority.
In 1994 the Trent Regional Health Authority became the Trent Regional Office of the NHS Executive. Within this regional structure, Nottingham Health Authority now provides local administration of hospitals in the Nottingham area.