The main body of the collection is correspondence from Dr. James D. Macgregor to his family in Scotland (but also to/from others) from both Sierra Leone and the Solomon Islands. The letters are largely in aerogramme form but there are also letters in conventional form with the original stamped and franked envelopes, as well as illustrative postcards and occasional ephemera. The content of the correspondence is largely descriptive of the locations and the work involved there, and to a degree there is family-oriented correspondence. The collection is composed of:
- Correspondence: c.197 letters from Sierra Leone, 1951-1957;
- Correspondence: c.613 letters from the Solomon Islands, 1957-1975;
- Tour reports to the Chief Secretary of the Western Pacific High Commission, 1960-1964;
- Police Medical/Postmortem Reports to the Sierra Leone Police, c.200 in number;
- Original book-file cover in which the Police Reports had been archived;
- Sierra Leone Protectorate Handbook, 1954.
In the material relating to Sierra Leone, 1953, are some programmes for the celebrations to be held at Makeni from 1-3 June 1953 in honour of the Coronation of Queen Elizabeth II. There is also a poster from the 'Committee of Gentlemen' about the staging of a dance on 5 June 1954 to mark the 'forthcoming Eid-ul-Fitri' with music from the 'Famous Cuban Swing Band'.
In the material relating to the Solomon Islands, there is a pamphlet about postal information issued by the Orient Line for the vessel SS Oronsay. Many of the early pieces of correspondence are written on Orient Line aerogrammes.
An edited version of all Macgregor's letters are contained on a CD within the collection.