Amongst the Les Coleman Collection is a significant collection of comics from North American underground [1968-1980] and alternative [1980-present] comic book movements. Perhaps the most significant component of the collection is Coleman's Robert Crumb material, which is possibly one of the largest in the UK. Other highlights in the collection include large collections of the work of Canadian comic book artist Julie Doucet and Serbian artist Aleksandar Zograf, complete runs of classic counter-cultural comics Arcade, Bijou Funnies and Raw. In addition to comics Coleman also acquired various signed and limited edition prints by comic book artists such as Charles Burns, Joe Coleman, Joost Swarte, Archer Prewitt and Aline-Kominsky Crumb. An admirer and champion of the art form Coleman organised and curated various comic exhibitions in his lifetime. A prominent British comic commentator and critic, Coleman was also in correspondence with various artists including Doucet, Zograf, Mack White, Jeff Johnson and Prewitt.
The second part of the Coleman collection is comprised of art, illustration and humour books from America, Australia, the UK and Europe (predominantly France and Belgium). Coleman's twin fascinations in this area were cartoons and surrealism, and his favoured artists range from the gentle newspaper gags of 'Larry' to the dark absurdist visions of Roland Topor. Other prominent artists in this part of the collection include Charles Addams, Edward Gorey, Saul Steinberg, HM Bateman, Glenn Baxter, Ivor Cutler, Maurice Henry, Sempé and Siné.
The third part of the collection is made up of Coleman's personal papers. Amongst this part of the collections there is a great deal of correspondence with his contemporaries in the art world such as painter, collaborator and teacher Patrick Hughes, the artist and children's' illustrator Tony Blundell, artist and colleague Charlie Holmes, artist and illustrator Chris Vine, French surrealist and publisher Marcel Mariën, and many more. Additionally there is a large collection of postcards and Christmas cards, many designed by the aforementioned artists. There is also some draft artwork and research material for a cartoon strip entitled 'Ying and Yang' which Coleman created in collaboration with Hughes. There is also a large collection of research material, primarily consisting of handwritten notes, annotated scans and photocopies, photographs, and sketches. Research material relates both to Coleman's teaching and curation careers.