Miss Copley had numerous relatives and a circle of highly connected female friends who are well represented among her correspondents, but by far the most prolific was her sister Maria, Countess Grey, who often wrote to her every day, accounting for 1,354 letters among these papers.
Miss Copley was involved in numerous religious and charitable enterprises, especially a Protestant mission to the Catholics of Ireland, based on a school and model farm at Ballinglen, Co. Mayo, and a Protestant educational mission to girls and women in Syria and Lebanon. These endeavours feature largely in her papers as does news of family and friends.