The records consist primarily of registers of the admission and discharge of patients (1895-1950). There are also registers of persons of unsound mind detained in the institution (1914-1947) and registers of sick, maternity and mental patients (1911-1950). Registers of births (1871-1947) and of deaths (1871-1948) are also present, as is a delivery ward register (1916-1942). In addition to these patient registers, the records include minutes of the Group House Committee (1957-1969) and half-yearly reports of the Medical Officer (1932-1948).
Records dealing with the Basford Union as an administrative unit were transferred to Nottinghamshire Archives Office. (These include some records of a medical nature, notably vaccination registers.) The records held at the University relate only to the admissions, discharges and treatment of patients while in Highbury Hospital.