The theme for this year's national Archive Awareness Campaign is 'Discovery: Archives in Science, Technology and Medicine', and we are celebrating the Nobel Prize-winning chemist and crystallographer Dorothy Crowfoot Hodgkin (1910–1994). Hodgkin's papers and correspondence are held by the Bodleian Library at the University of Oxford, where she carried out her pioneering research.
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Born Dorothy Crowfoot, she developed an interest in chemistry and crystals while still at junior school, and carried out experiments at home in the attic. She went on to study chemistry at Oxford's Somerville College, one of the rare women science students there, and carried out her research in X-ray crystallography in the University's Natural History Museum.
After gaining a degree with first class honours, Hodgkin then went to Cambridge as a research student in the laboratory of physicist John Desmond Bernal. After completing her doctorate, she returned to Oxford as a Fellow of Somerville College and set up her own laboratory.
Penicillin had been discovered in 1929, and the onset of war brought urgent research into this antibiotic. Dorothy revealed its three-dimensional structure in 1944. This and much of her other work was published under the name Dorothy Crowfoot - although she married in 1937, Hodgkin still published under her maiden name until 1949.
After the war, Hodgkin helped form the International Union of Crystallography, of which she was President from 1972-1975. In 1956 she uncovered the structure of B12, a vitamin essential for blood formation.
In 1964 she was awarded the Nobel Prize for Chemistry, for the "determinations by X-ray techniques of the structures of important biochemical substances", making her the only British woman to date to receive a Nobel Prize for science. Hodgkin went on to determine the structure of insulin in 1969.
In 1970 she was elected Chancellor of the University of Bristol, normally a purely honorary position, but Hodgkin helped establish a scholarship for students from the developing world.
From the 1960s she attended the Pugwash Conferences on Science and World Affairs, and served as President from 1976-1988. Pugwash was founded in 1955 by Bertrand Russell, Albert Einstein, and others, with the aim of bringing together scientists from East and West to discuss disarmament.
Hodgkin was elected Fellow of the Royal Society (FRS) in 1947, and in 1965 she became only the second woman to be awarded the Order of Merit.
Sources: Georgina Ferry, "Hodgkin, Dorothy Mary Crowfoot (1910–1994), chemist and crystallographer", Oxford Dictionary of National Biography; Dr Tim Powell, Papers and Correspondence of Dorothy Crowfoot Hodgkin, 1910-1994.
Above, right: Dorothy Hodgkin in the Abbot's Kitchen adjacent to the Oxford Natural History Museum; photo Cipanlaknat, from Wikimedia Commons.
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